Tạp chí Y học Thảm hoạ và Bỏng

Preoperative anxiety in pediatric burn surgery: Evaluation using the modified yale preoperative anxiety scale

2025-11-10T08:33:15+00:00

Objective and methodology: This study aimed to assess the preoperative anxiety status of pediatric burn patients prior to surgery through a prospective observational design with repeated measures conducted at Le Huu Trac National Burn Hospital (Hanoi, Vietnam) between January and October 2025. 135 children aged 2 - 10 years (ASA I - II) with TBSA (1 - 15%) undergoing elective debridement or skin grafting under laryngeal mask airway anesthesia were enrolled. Anxiety was measured with the modified Yale Preoperative Anxiety Scale (mYPAS) at three time points (T1: ward; T2: parental separation; T3: before induction). Results: Mean mYPAS scores significantly increased across time points: 38.37 ± 6.66 at T1, 49.36 ± 8.11 at T2, and 51.23 ± 8.52 at T3. Preschool children (< 72 months) exhibited higher anxiety than school-aged children (≥ 72 months) at all time points (p < 0.05). Children with previous surgical exposure also demonstrated higher anxiety levels compared with those undergoing their first procedure (p < 0.05). Conclusion: Preoperative anxiety was highly prevalent among pediatric burn patients, especially in younger children and those with prior surgical experience. Anxiety levels increased significantly during parental separation and anesthesia induction. These findings emphasize the need for routine assessment using validated behavioral tools such as mYPAS and for implementing age-appropriate anxiety-reduction strategies in perioperative care

In vitro evaluation of antibacterial activity of berberine nano gel on standard bacterial strains associated with burn wound infections

2025-12-18T09:00:01+00:00

Objective: To evaluate the In vitro antibacterial activity of berberine nanogel against reference bacterial strains and compare it with a reference control. Subjects and methods: In vitro experimental design. Antibacterial activity was quantified using the agar disk diffusion method (zone of inhibition, mm). Time-kill assays were conducted using twofold serial dilutions (from 1/2 to 1/128) with with bacterial growth assessed at 2, 6, and 24 hours for Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. Results: The berberine nanogel produced zones of inhibition against both Gram-positive and some Gram-negative bacteria. Specifically: E. coli 17.11 ± 1.44 mm vs. the reference control 23.49 ± 2.16 mm (p < 0.001); P. aeruginosa 14.14 ± 1.61 mm vs. 14.25 ± 1.88 mm (p > 0.05); Acinetobacter sp. 19.79 ± 1.37 mm vs. 10.59 ± 1.19 mm (p < 0.001); Enterobacter sp. 15.26 ± 1.58 mm vs. 24.26 ± 0.97 mm (p < 0.001). For Gram-positive bacteria, S. aureus achieved 16.47 ± 1.54 mm vs. 11.20 ± 1.37 mm (p < 0.001). In time - kill testing, no bacterial growth was observed after 24 hours at dilutions ≥1/16 for E. coli and P. aeruginosa, and at ≥ 1/32 for S. aureus. At higher concentrations (≥1/4), early inhibition/bactericidal activity was evident as early as 2 hours. Conclusion: Berberine nanogel demonstrated significant In vitro antibacterial activity, with pronounced effects against S. aureus and Acinetobacter sp., and efficacy comparable to the reference control against P. aeruginosa.

Effects of TGF-β and dim on the secretion of growth factors into the culture medium by umbilical cord - derived mesenchymal stem cells

2025-12-18T09:06:19+00:00

Purpose: Mesenchymal stem cells (MSCs) and their secretome have been demonstrated to play an important role in regenerative medicine. In particular, the secretome, which consists of soluble factors and extracellular vesicles, including microvesicles and exosomes, is emerging as a promising cell-free alternative to MSCs because it is considered safer than cells while retaining comparable efficacy. However, the composition of this secretome is highly sensitive and influenced by multiple factors, including the type and source of the secreting cells, their physiological state, and the stimulating factors during cell culture. This study evaluates the expression of several growth factors secreted into the conditioned medium by umbilical cord-derived MSCs (UCMSCs) under stimulation with TGF-β and 3,3′-diindolylmethane (DIM). Subjects and methods: UCMSCs were cultured at passage 5 (P5) and primed with TGF-β, DIM, and a combination of TGF-β and DIM. Conditioned media were collected and analyzed for the levels of key growth factors, including fibroblast growth factor-2 (FGF-2), hepatocyte growth factor (HGF), platelet-derived growth factor-BB (PDGF-BB), and vascular endothelial growth factor-A (VEGF-A), using Luminex assays. Results: Results showed that FGF-2 and HGF expression remained consistent across all groups, with no significant differences, except that the HGF level in the TGF-β and DIM-primed group is greater than that in the from TGF-β-primed group. In contrast, TGF-β significantly increased the secretion of PDGF-BB and VEGF-A by USMCS compared with the control group (p < 0.05), highlighting its strong modulatory effect. DIM did not significantly alter growth factor levels. Additionally, the combination of TGF-β and DIM did not produce synergistic effects and even attenuated PDGF-BB secretion compared with TGF-β. Conclusion: These findings demonstrate that TGF-β is a potent regulator of UCMSC secretome, enhancing the release of growth factors associated with tissue regeneration and angiogenesis, whereas DIM alone exerts minimal influence. Additionally, the absence of synergistic effects between TGF-β and DIM suggests a complex interplay between cellular signaling pathways. This study underscores the potential of TGF-β preconditioning as a strategy to optimize UCMSC secretome for regenerative medicine applications.

Clinical characteristics, paraclinical features, and treatment outcomes of continuous renal replacement therapy in patients with multiple organ dysfunction syndrome due to septic shock at the intensive care unit of Military Hospital 175

2025-10-27T17:40:06+00:00

Objective: To describe the clinical and paraclinical characteristics and evaluate the outcomes of continuous renal replacement therapy (CRRT) in patients with multiple organ failure due to septic shock. Subjects and methods: This was a prospective, longitudinal, uncontrolled, cross-sectional descriptive study conducted on 47 patients diagnosed with multiple organ failure due to septic shock, treated in the Intensive Care Unit of Military Hospital 175 from June 2023 to December 2024. Results: The study included 47 patients with multiple organ failure due to septic shock (63.8% male, mean age 58.3 ± 14.2 years), predominantly with community-acquired infections (76.6%). The mean APACHE II and SOFA scores were 22.4 ± 5.1 and 11.2 ± 3.7, respectively; mean blood lactate was 4.3 ± 2.1 mmol/L. CRRT significantly reduced the number of failed organs in the survival group (from 2.9 ± 0.9 to 1.6 ± 0.8, p < 0.001), but not in the non-survival group (p = 0.08). The shock reversal rate was 57.4%, the mortality rate was 44.7%, and the mean ICU stay was 9.5 ± 4.2 days. Early initiation of CRRT (≤ 24 hours) was associated with improved survival (64.3% vs. 21.1%, p < 0.05). Early initiation of CRRT within 24 hours was an independent protective factor (OR = 0.39; 95% CI: 0.15-0.98; p = 0.045), whereas APACHE II score (OR = 1.11; 95% CI: 1.01-1.28; p = 0.04), SOFA score (OR = 1.21; 95% CI: 1.05-1.48; p = 0.006), and blood lactate level (OR = 1.28; 95% CI: 1.04-1.68; p = 0.03) were independent risk factors. Conclusion: Early CRRT within 24 hours is an independent protective factor that reduces the risk of mortality. In addition, APACHE II and SOFA scores, along with blood lactate levels, are independent risk factors with prognostic value for mortality in patients with septic shock.

Preliminary evaluation of the therapeutic effectiveness of silicone pressure dressing (Gelzone) in the prevention of post-burn scarring

2025-12-18T09:14:38+00:00

Objective: To conduct a preliminary evaluation of the effectiveness of silicone pressure dressing (Gelzone) in preventing post-burn scars. Subjects and methods: A prospective descriptive, uncontrolled clinical trial was carried out on 30 patients with post-burn sequelae scars of the extremities who presented at the Center for Plastic and Reconstructive Surgery - Le Huu Trac National Burn Hospital, between August 2024 and August 2025. Results: Most patients were female (66.7%), with a mean age of 29.2 ± 13.8 years. Thermal injury accounted for the majority of burn causes (86.7%). Scars were predominantly located in the lower extremities (76.7%), especially on the legs (56.7%). Hypertrophic scars were the most common type (73.3%), with 76.7% of patients experiencing both pain and pruritus. The mean VAS pain score significantly decreased from 6.8 ± 1.5 before treatment to 1.3 ± 1.4 at 6 months (p < 0.001). Vancouver Scar Scale parameters, including pigmentation, vascularity, pliability, and height, showed statistically significant improvement after treatment, particularly at 3 and 6 months (p < 0.001). Conclusion: Gelzone silicone pressure dressing demonstrated promising effectiveness in improving pain and clinical characteristics of post-burn scars. This method appears to be safe and effective, warranting broader clinical application and further investigation.

Study on changes in serum sodium levels in patients with intracerebral hemorrhage and related factors

2025-10-27T18:00:48+00:00

Objective: To describe the variations in serum sodium levels in patients with intracerebral hemorrhage (ICH) and to analyze associated factors. Subjects and methods: A prospective longitudinal descriptive analytical study was conducted on 112 patients diagnosed with ICH and treated at the Intensive Care Unit of Military Hospital 175 from June 2023 to December 2024. Results: This study evaluated sodium disturbances in 112 ICH patients. Hyponatremia was observed in 59 patients (52.7%), primarily of mild severity (52.6%). The main causes were syndrome of inappropriate antidiuretic hormone secretion (SIADH, 35.6%) and cerebral salt-wasting syndrome (CSWS, 25.4%), while 39% of cases had unidentified etiologies. Hyponatremia was significantly associated with hypertension (OR = 2.6, p = 0.036), smoking (OR = 2.4, p = 0.048), and large hematoma volume (> 60 cm³, p = 0.028). Frontal lobe lesions showed a potential association with hyponatremia (OR = 3.1, p = 0.076). Conclusion: Hyponatremia is common among patients with intracerebral hemorrhage and is associated with hypertension, smoking, and hematoma volume. SIADH and CSWS are the leading causes; however, further research is needed to clarify the cases with unknown etiology.

Antimicrobial resistance profiles of Staphylococcus epidermidis septicemia in Vietnamese cancer patients

2025-12-18T09:25:29+00:00

Staphylococcus epidermidis is an important cause of bloodstream infections and a cause of morbidity and mortality in cancer patients. The antimicrobial resistance profiles of S. epidermidis septicemia in Vietnamese cancer patients are limited. We surveyed all S. epidermidis blood culture isolates from Vietnamese cancer patients at the Tan Trieu National Cancer Hospital, from 2020 to 2024. A total of 11 S. epidermidis isolates were identified and antibiotic susceptibility testing was employed. Methicillin resistance was detected in 4/11 of all isolates; all were sensitive to vancomycin, nitrofurantoin, linezolid, quinupristin-dalfopristin; however, all were resistant to benzylpenicillin, oxacillin; 7/11 of isolates were resistant to clindamycin, erythromycin, and trimethoprim-sulfamethoxazole; All of the isolates (11/11) are multidrug resistance. Vancomycin, nitrofurantoin, linezolid, and quinupristin-dalfopristin are effective antimicrobial agents in treating S. epidermidis septicemia in Vietnamese cancer patients. The high level of methicillin and multidrug resistance limited the therapeutic options in Vietnamese cancer patients are causes of concern.

Clinical case report: application of a combination of advanced techniques in management of a soldier with severe ordnance burns and concomitant inhalation injury

2025-12-18T09:30:47+00:00

Introduction: The combination of extensive burns, inhalation injury and polytrauma represents one of the greatest challenges in emergency and disaster medicine, associated with high mortality rates due to complications such as shock, acute respiratory distress syndrome (ARDS), multiple organ dysfunction and sepsis. We report a clinical case of the successful resuscitation and management of a soldier who sustained 80% total body surface area (TBSA) ordnance burns (including 50% full-thickness burns), complicated by severe inhalation injury and complex polytrauma. Case Presentation: A 21-year-old male soldier sustained burns and polytrauma from an ordnance-related incident. Following initial resuscitation and aeromedical evacuation to the Le Huu Trac National Burns Hospital, an aggressive, multimodal treatment strategy was implemented. Within the first 48 hours, the patient underwent extensive surgical excision of the burn eschar over 50% of his TBSA. In the subsequent course of treatment, due to unsalvageable crush injuries, the patient required amputation of the distal third of the right lower leg and the distal third of the right arm for source control of infection. Advanced techniques were applied synchronously, including treatment of the inhalation injury with nebulized Heparin and N-Acetylcysteine, invasive hemodynamic monitoring with the PiCCO system, Negative Pressure Wound Therapy (NPWT) and wound coverage using autologous skin grafts combined with a non-cultured autologous cell suspension. After 3 months of treatment and 6 surgical procedures, the patient achieved complete wound coverage. He survived the critical phase, successfully avoiding common high-mortality complications such as acute renal failure, sepsis, multiple organ dysfunction and ARDS and was subsequently transferred to the rehabilitation phase. Conclusion: The coordinated chain of care-from pre-hospital stabilization for airlift to the synchronized application of advanced technologies at a specialized center-was critical for the patient's survival through the critical phase. This case underscores the decisive role of an aggressive, proactive and technology-driven treatment strategy in improving outcomes for patients with catastrophic burn injuries.

Reconstruction of lower leg burns with achilles tendon and tibial exposure using posterior tibial artery perforator flap: A report of six cases

2025-09-30T15:29:54+00:00

Background: Deep burns of the lower leg and ankle caused by motorcycle exhausts frequently lead to exposure of tendon or bone, where skin grafts alone are insufficient. The posterior tibial artery perforator (PTAP) flap provides reliable vascularized tissue with minimal donor morbidity and may be a valuable reconstructive option. Methods: From June 2023 to September 2025, six patients with full-thickness lower leg burns and exposed Achilles tendon and tibia, underwent reconstruction with PTAP flaps at the National Burn Hospital, Hanoi. Flaps were designed with hand-held Doppler-guided perforator mapping. Clinical outcomes were evaluated with regard to flap survival, donor site management, and complications. Results: Defect sizes ranged from 4 × 4 cm to 12 × 8 cm, with flap dimensions ranged from 9 × 5 cm to 16 × 10 cm and rotation arcs of 1100 - 1800. Donor sites were closed with split-thickness skin grafts. Four flaps survived completely, while two developed partial necrosis that healed after secondary intervention. No total flap loss occurred. All patients achieved stable coverage, maintained limb function, and reported satisfactory cosmetic outcomes. Conclusion: The PTAP flap proved to be a reliable option for reconstruction of complex lower leg burns with exposure of the Achilles tendon or distal tibia

Application of the external-pedicled and inferior-pedicled cheek rotation flaps in the reconstruction of skin defects at the medial and lateral canthi of the lower eyelid

2025-12-18T09:39:24+00:00

the inferior-pedicled cheek rotation flap in reconstructing skin defects of the lower eyelid, particularly at the medial and lateral canthal regions - areas that present significant reconstructive and aesthetic challenges. Subjectsand methods: A case series of patients with lower-eyelid skin defects following tumor excision, trauma, or burn injury. Defects ranged from 1-3 cm and involved the medial or lateral canthus without full-thickness eyelid loss. Reconstruction was performed using either a lateral-pedicled cheek rotation flap based on branches of the facial artery or an inferior-pedicled cheek rotation flap based on the angular arterial system. Outcomes assessed included flap survival, eyelid position, contour, complications, and aesthetic satisfaction over a 1-3-month follow-up. Results: All flaps survived completely with good color and thickness match to the lower-eyelid region. No cases of ectropion, lid retraction, or flap necrosis occurred. Scars were well concealed within natural facial creases. Functional and aesthetic outcomes were rated as good to excellent in all patients. Conclusion: Lateral- and inferior-pedicled cheek rotation flaps provide a reliable, simple, and aesthetically favorable option for reconstructing lower-eyelid skin defects involving both the medial and lateral canthi. Their robust vascularity, tissue match, and minimal risk of eyelid distortion make them an effective method for periocular reconstruction.

Successful treatment of a patient with 98% total body surface area burns complicated by acute respiratory distress syndrome and septic shock

2025-12-18T09:44:56+00:00

Septic shock and acute respiratory distress syndrome (ARDS) are common complications that significantly increase mortality in patients with severe burns. Advances in hemodynamic resuscitation, rational antibiotic therapy, continuous blood purification using adsorptive membranes, prone-position ventilation with low tidal volumes, and the combined use of aerosolized and intravenous antibiotics in the treatment of pneumonia caused by multidrug-resistant gram-negative bacteria have markedly improved survival outcomes in severe burn patients.

Submental flap reconstruction of perioral electrical burn defects: A case report

2025-12-18T09:49:54+00:00

Electrical burns involving the perioral region are uncommon but often lead to full-thickness soft tissue loss, impairing both function and aesthetics. Optimal reconstructive strategy selection is pivotal, particularly challenging in settings without microsurgical resources. The submental flap provides a reliable, well-vascularized tissue source with favorable color and texture match and a concealed donor-site scar. We present a case of a male patient who sustained a low-voltage electrical burn resulting in a perioral soft tissue defect, successfully reconstructed with a pedicled submental flap. At three months postoperatively, the flap remained fully viable, with preserved oral competence, satisfactory aesthetic appearance, and no donor-site morbidity. This case underscores the submental flap as a safe, technically straightforward, and effective option for small to moderate perioral defects caused by electrical injury.

Effectiveness of autologous platelet-rich plasma in the treatment of difficult-healing pressure ulcers

2025-12-18T09:58:58+00:00

Objectives: To evaluate the efficacy of autologous platelet-rich plasma (PRP) in the treatment of refractory pressure injuries and its effect on wound healing time and quality of life of patients. Subjects and methods: A random number table method was used to group 102 patients with refractory pressure injuries into either a control group (CG) (51 cases) receiving negative pressure wound therapy (NPWT) or a study group (SG) (51 cases) receiving NPWT+PRP. Results: The total efficacy rate in the SG (92.16%) was higher than that in the CG (76.47%) (p < 0.05). The SG exhibited lower visual analog scale (VAS) scores and pressure ulcer scale for healing (PUSH) scores, smaller wound sizes and depths, and shorter wound healing times than the CG after 21 days of treatment (p < 0.05). After 6 months of treatment, the SG scored higher than the CG on the psychological, physiological, social functions, and daily activity domains on the World Health Organization Quality of Life (WHOQOL-BREF) scale (p < 0.05). The incidence of postoperative complications in the SG (13.73%) was not significantly different from that of the CG (7.84%) (p > 0.05). Conclusion: In the treatment of refractory pressure injuries, PRP can accelerate wound healing, reduce wound pain, shorten the treatment cycle and improve the quality of life of patients without increasing complications.

The analgesic efficacy of Levobupivacaine - Fentanyl via patient-controlledepidural analgesia after renal transplantation

2025-11-13T17:22:02+00:00

Objective: Evaluating the analgesic effect of patient-controlled epidural analgesia (PCEA) using a mixture of levobupivacaine 0.1% and fentanyl 2 µg/ml after renal transplantation. Methodology: A prospective, descriptive, longitudinal study was conducted on 50 patients (n=50) over 18 years old (ASA II-IV) who underwent renal transplantation (RT) surgery at 103 Military Hospital from August 2023 to October 2023. The PCEA solution comprised 0.1% levobupivacaine combined with 2 µg/ml fentanyl. Analgesic efficacy was assessed using the Visual Analog Scale (VAS) score both at rest and during movement (coughing) across time points up to 72 hours post-surgery. Results: The PCEA method provided effective pain control. Mean VAS scores significantly decreased from baseline (H0: 7.1 ± 1.08) to H72 (0.26 ± 0.29 at rest; 0.65 ± 0.49 during movement) (p < 0.001). The average percentage of successful demand requests (A/D ratio) was 85.53 ± 5.48%. Hemodynamic parameters (HR, SBP, MAP) showed statistically significant reductions (p < 0.001) compared to H0 but remained stable within safe clinical limits throughout the monitoring period. The average respiratory rate decreased from 23.90 ± 2.49 breaths/min (H0) to 14.64 ± 1.60 breaths/min (H72). No respiratory depression or motor blockade (100% Bromage M0) was observed. Common adverse drug reactions (ADRs) included nausea/vomiting (16.0%) and itching (12.0%). Patient satisfaction was high, with 88% very satisfied and 12% satisfied. Conclusion: PCEA utilizing a mixture of levobupivacaine 0.1% and fentanyl 2 µg/ml is a highly effective and satfety method for managing acute postoperative pain after renal transplantation surgery, achieving stable, low VAS scores below the clinically accepted threshold throughout the 72-hour observation period.

Current status of peripheral intravenous catheter (pivc) insertion andmanagement in pediatric patients and related factors at the pediatrics center,Thai Nguyen National Hospital

2025-09-28T15:49:44+00:00

Objective: To assess the current status of peripheral intravenous catheter (PIVC) insertion, maintenance, and management in pediatric patients, and to identify associated factors. Subjects and methods: A prospective study was conducted comprising 323 observations of PIVC insertion and care in children at the Pediatric Center, Thai Nguyen National Hospital. Results: 52.4% of cases were classified as having difficult venous access, and only 20.7% were rated as “good” for venous access. In 98.8% of observations, nursing performance in the PIVC insertion protocol was rated “good”; 1.2% were “fair,” and none were “poor.” Mild pain or slight erythema at the insertion site occurred in 52.9% of children. The mean PIVC dwell time was 3 days. Child age, nursing experience, management of difficulties encountered, and procedure duration were each significantly associated with venous access quality (p < 0.05). Phlebitis was significantly associated with child age, nursing experience, troubleshooting, and dressing tubing condition (p < 0.05). Conclusions: Despite high protocol adherence, achieving venous access in children remains challenging; child age, nursing experience, procedure time, difficulty management are key correlates. Strengthen technical training in PIVC for clinical nurses and standardize with rigorous monitoring of insertion and care processes. Integrate routine Visual Infusion Phlebitis (VIP) scoring into nursing records to enable early complication alerts and catheter replacement at predefined thresholds.

Determinants of Quality of Life Among Older Adults in a Peri-Urban Community of Da Nang: A Multivariable Analysis

2025-12-18T10:03:11+00:00

Background: Population aging is accelerating in Viet Nam, increasing the need to better understand factors influencing quality of life (QoL) among older adults. This study examined determinants of QoL in a peri-urban community of Da Nang City. Subject and methods: A cross-sectional survey was conducted with 253 older adults selected through systematic random sampling. QoL was assessed using a validated 65-item instrument. Univariate analyses identified potential correlates, and multivariable linear regression determined independent predictors. Results: Five variables were independently associated with QoL: educational attainment (β = 8.14; p = 0.016), living alone (β = -13.86; p = 0.011), leisure travel in the past year (β = 14.22; p = 0.003), chronic disease (β = -18.93; p < 0.001), and recent illness (β = -7.97; p = 0.025). The final model explained 38.1% of QoL variance. Conclusion: QoL among older adults is primarily influenced by social and health factors. Enhancing social support, promoting leisure engagement, and strengthening chronic disease management may improve well-being in aging populations.

Impact of Pre hospital First Aid on Burn Outcomes: Insights from the 2024 National Burn Hospital Database

2025-12-18T10:07:02+00:00

Background: Burn injuries remain a major public health concern in low and middle income countries, where limited awareness of first aid and delayed access to specialized care contribute to poor outcomes. This study aimed to describe the epidemiological characteristics, pre hospital first aid practices, and treatment outcomes among burn patients in Northern Vietnam. Subjects and methods: A retrospective descriptive study was conducted among 750 burn patients admitted to the National Burn Hospital in 2024. Sociodemographic characteristics, burn etiology, clinical severity, first aid practices, and treatment outcomes were extracted from medical records. Associations between first aid quality and clinical outcomes were analyzed. Results: The majority of patients were male (66.0%) and of working age. Thermal burns were the most common etiology (72.0%), followed by electrical (20.0%) and chemical burns (8.0%). Although 64.0% of patients received some form of first aid, only 34.7% received appropriate cooling with clean water, while 13.3% applied harmful substances. Timely first aid within 10 minutes occurred in only 24.0% of cases. Correct first aid was strongly associated with improved outcomes, including lower complication rates (15.4% vs. 34.7%), lower mortality (2.3% vs. 6.5%), and shorter hospital stays (14.2 vs. 21.0 days). Surgical intervention and ICU care were required in 41.3% and 24.0% of patients, respectively. Conclusion: Burn injuries in Northern Vietnam predominantly affect working age adults and are frequently associated with inadequate or inappropriate first aid. Early, evidence based first aid particularly cooling with clean water is strongly associated with reduced complications, mortality, and length of hospital stay. Strengthening community education, improving occupational safety, and enhancing pre hospital and referral systems are essential to reducing the burden of burns in the region.

Anesthesia management for organ procurement in brain-dead donors: Two case reports and key considerations

2025-10-27T18:04:18+00:00

Organ donation procedures have become more frequent in Vietnam as the need for transplants is increasing and changes in organ donation policies. Intraoperative management during organ procurement after brain death requires addressing the unique physiological challenges of brain death while optimizing the viability of the organs intended for transplantation. The anesthesiologist’s role is critical and can directly impact the success of organ recovery and subsequent transplantation outcomes. This paper outlines the intraoperative management of two brain-dead donors recently performed at Military Hospital 103 and explores key considerations for anesthesiologists involved in organ procurement.

Operation outcomes of metacarpal and phalangeal fracture fixation usingplates and screws at Thai Nguyen Central Hospital

2025-10-25T10:54:19+00:00

Objective: To evaluate the surgical outcomes of metacarpal and phalangeal fracture fixation using plates and screws at Thai Nguyen Central Hospital. Subjects and methods: A retrospective descriptive cross-sectional study was conducted on 120 patients with metacarpal and phalangeal fractures treated at Thai Nguyen Central Hospital. Results: Postoperatively, 96.7% of fractures achieved anatomical alignment with complete reduction. According to the Larson Bostman criteria for early postoperative evaluation, 84.2% of patients had excellent results, 15% good, and 0.8% fair. After three months, bone union was achieved in 98.3% of cases, with delayed union observed in two patients (1.7%). At the three-month follow-up, 85% of patients demonstrated good hand mobility, while 15% showed mild movement limitation. Based on the Belsky criteria for overall outcomes at three months, 79.2% of patients had excellent results, 20% good, and 0.8% not good. Conclusion: Bone fixation with plates and screws is an effective surgical method for treating metacarpal and phalangeal fractures.

Laparoscopic cholecystectomy outcomes in the treatment of gallbladderstones at Thai Nguyen Central Hospital

2025-10-25T10:45:25+00:00

Objective: To evaluate the outcomes of laparoscopic cholecystectomy for the treatment of gallbladder stones at Thai Nguyen Central Hospital from January 2023 to May 2025. Subjects and research methodology: A retrospective and cross-sectional descriptivestudy was conducted on 120 patients diagnosed with gallbladder stones who underwent laparoscopic cholecystectomy. Results: Most patients required postoperative analgesics for less than three days (68.3%). The mean time to first passage of flatus was 0.7 days (equivalent to 16.8 hours). The mean postoperative hospital stay was 6.25 days, and the average total duration of treatment was 10.28 days. Only one patient (0.8%) developed a postoperative wound infection. Overall, 95% of patients achieved good surgical outcomes, while 5% had moderate results; no poor outcomes were reported. Conclusion: Laparoscopic cholecystectomy is an effective and safe surgical method for the management of gallbladder stones at Thai Nguyen Central Hospital.