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To evaluate safety of the adsorption hemofiltration technique for treatment of septic shock in severe burn patients
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Tóm tắt
Objectives: Evaluating the safety of continuous hemofiltration using an adsorbent membrane to treat septic shock in severe burns patients.
Subjects and methods: The study describes 55 episodes of septic shock in 38 severe burn patients (16 - 60 years old) treated at the Intensive Care Unit, Le Huu Trac National Burn Hospital from January 2023 to June 2024.
Results: The total number of filters used was 247, of which 8 filters had frozen membranes (3.2%), the average life of the filter was 15.87 hours. There were no cases of systolic blood pressure falling below 90 mmHg when entering the filter. During continuous veno-venous hemodiafiltration (CVVHDF): Body temperature was always within allowable limits; there were no differences in blood potassium levels, blood protein and albumin concentration, and hypocoagulation disorders at all time points (p > 0.05); blood sodium concentration decreased significantly to normal limits (p < 0.01).
There was no difference in hypocoagulation status between time points (p > 0.05). There was 1 case of bleeding at the dialysis catheter fixation site (1.82%) and 2 cases of bleeding at the skin graft lesion requiring hemostatic treatment (3.62%).
Conclusion: There were no differences in blood potassium levels, blood protein and albumin concentration, and hypocoagulation disorders at all time points.
Chi tiết bài viết
Từ khóa
Severe burns, septic shock, CVVHDF
Tài liệu tham khảo
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