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Date Published: 28/02/2025
Online Published: 28/02/2025
Abstract Views: 263
Views article details: 142
DOI: https://doi.org/10.54804/yhthvb.1.2025.386
Issue
No. 1 (2025)
Section
Articles
How to Cite
Nguyen, T. D., Chu, A. T., & Tran, N. D. (2025). Studying effects of Polyhexamethylene Biguanide Hydrochloride (Latex HB®) in the treatment of infected wounds. Journal of Disaster Medicine and Burn Injuries, 1, 44-54. https://doi.org/10.54804/yhthvb.1.2025.386

Studying effects of Polyhexamethylene Biguanide Hydrochloride (Latex HB®) in the treatment of infected wounds

Nguyen Tien Dung1,, Chu Anh Tuan1, Tran Ngoc Diep1
1 Le Huu Trac National Burn Hospital

Main Article Content

Abstract

Objective: Evaluation of the effect of Polyhexamethylene biguanide hydrochloride (Latex HB®) in the treatment of infected wounds
Subjects and methods: Twenty-four infected wounds of 20 inpatients at the Wound Healing Center - National Burn Hospital, from July to August 2024. The wounds were washed with Latex HB®. Evaluating the progress of the wound beds, identifying bacteria and determining the number of bacteria per 1 cm2 of the wound surface, at the time before (T0), after 7 days (T1), and after 14 days (T2) using Latex HB®.
Results: Wound exudate and swelling reduced. The proportion of wounds with epithelialization and good granulation tissue increased. The wound size was reduced. Latex HB® did not cause allergic reactions. The rate of positive bacterial culture was reduced: 15 wounds (62.5%) at T0, 10 wounds (41.7%) at time T1, and T2 had only 4 wounds (16.7%). The number of S.aureus and P.aeruginosa/1cm2 of wound surface was significantly reduced at the study time points.
Conclusion: Polyhexamethylene biguanide hydrochloride (Latex HB®) had hypoallergenic, anti-inflammatory effects, and helped to eliminate wound surface bacteria, to stimulate and to promote wound healing.

Article Details

Keywords

Infected Wound, Polyhexamethylene Biguanide Hydrochloride, Biofilm

References

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