Septic shock with dermatitis and necrotizing myositis due to Vibrio vulnificus infection (Case report)
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Tóm tắt
Vibrio vulnificus (V. vulnificus) is a gram-negative bacterium that can cause serious, potentially fatal infections. V. vulnificus causes three distinct syndromes: Overwhelming primary septicemia caused by consuming contaminated seafood, wound infections acquired when an open wound is exposed to contaminated warm seawater, and gastrointestinal tract-limited infections. Case-fatality rates are higher than 50% for primary septicemia, and death typically occurs within 72 hours of hospitalization.
Risk factors for V. vulnificus infection include chronic liver disease, alcoholism, and hematological disorders. When V. vulnificus infection is suspected, appropriate antibiotic treatment and surgical interventions should be performed immediately. Third-generation cephalosporin with doxycycline, or quinolone with or without third-generation cephalosporin, may be potential treatment options for patients with V. vulnificus infection.
Chi tiết bài viết
Từ khóa
Septic shock, infection
Tài liệu tham khảo

2. Ma KA, Lee SM, Kim MS, et al. Emergency debridement with empirical antibiotics treatment for clinically diagnosed Vibrio sepsis. Korean J Infect Dis 1997; 29:297- 303.

3. Kim HS, Kim DM, Neupane GP, et al. Comparison of conventional, nested, and real-time PCR assays for rapid and accurate detection of Vibrio vulnificus. J Clin Microbiol 2008; 46:2992-2998.

4. Lee JY, Kim SW, Kim DM, Yun NR, Kim CM, Lee SH. Clinical usefulness of real-time polymerase chain reaction for the diagnosis of Vibrio vulnificus infection using skin and soft tissues. Am J Trop Med Hyg 2017; 97:443-446.

5. Klontz KC, Lieb S, Schreiber M, Janowski HT, Baldy LM, Gunn RA. Syndromes of Vibrio vulnificus infections. Clinical and epidemiologic features in Florida cases, 1981- 1987. Ann Intern Med 1988; 109:318-323.

6. Bilton BD, Zibari GB, McMillan RW, Aultman DF, Dunn G, McDonald JC. Aggressive surgical management of necrotizing fasciitis serves to decrease mortality: a retrospective study. Am Surg 1998; 64:397-400.

7. Bowdre JH, Hull JH, Cocchetto DM. Antibiotic efficacy against Vibrio vulnificus in the mouse: superiority of tetracycline. J Pharmacol Exp Ther 1983; 225:595-598.

8. Daniels NA. Vibrio vulnificus oysters: pearls and perils. Clin Infect Dis 2011;52: 788-792.

9. Bross MH, Soch K, Morales R, Mitchell RB. Vibrio vulnificus infection: diagnosis and treatment. Am Fam Physician 2007; 76:539-544.

10. Wright AC, Simpson LM, Oliver JD. Role of iron in the pathogenesis of Vibrio vulnificus infections. Infect Immun 1981; 34:503-507.
