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The effectiveness of negative pressure wound therapy in the treatment of deep burn injuries after necrotic debridement and autologous skin grafting
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Abstract
Objective: To evaluate the effectiveness of negative pressure wound therapy (NPWT) in treating deep burns after autologous skin grafting.
Subjects and methods: This prospective controlled study was conducted on 20 patients with deep burns, divided into two groups. The NPWT group included 10 patients treated with NPWT at pressures ranging from -125 mmHg to -80 mmHg for 5 days post-skin grafting. The control group consisted of 10 patients receiving conventional dressing (CD). The primary outcomes assessed were the graft take rate on day 7 and day 14 after surgery, along with the incidence of complications such as infection and hematoma.
Results: The graft take rate in the NPWT group was 90.9% on day 7 and 87.9% on day 14, significantly higher than the control group, which had rates of 86.3% and 80.7%, respectively (p < 0.05). Regarding complications, no cases of infection or hematoma were observed in the NPWT group, whereas the control group had infection and hematoma rates of 10%. However, one case of graft site bleeding was recorded in the NPWT group.
Conclusion: NPWT is a safe and effective method for managing deep burns after autologous skin grafting, enhancing graft survival and reducing the risk of complications.
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Keywords
Negative pressure wound therapy (NPWT), necrotic debridement and autologous skin grafting
References
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