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Date Published: 28/02/2021
Online Published: 28/02/2021
Abstract Views: 407
Views Full article: 76
Issue
No. 1 (2021)
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Articles
How to Cite
Ngo, T. H., Nguyen, H. A., & Nguyen, N. L. (2021). Evaluating the efficacy of nebulized Heparin combined with Pulmicort and N-acetylcysteine in ICU burn patients with inhalation injury, Le Huu Trac National Burn Hospital. Journal of Disaster Medicine and Burn Injuries, 1, 28-34. https://jbdmp.vn/index.php/yhthvb/article/view/25

Evaluating the efficacy of nebulized Heparin combined with Pulmicort and N-acetylcysteine in ICU burn patients with inhalation injury, Le Huu Trac National Burn Hospital.

Ngo Tuan Hung1,, Nguyen Hai An1, Nguyen Nhu Lam1
1 Le Huu Trac National Burn Hospital

Main Article Content

Abstract

Methods: A intervention study on 29 adult patients with inhalation injury and mechanical ventilation in the ICU - Le Huu Trac National Burn Hospital from 08/2019 to 06/2020.
The patients were randomized into two groups:
Group 1: Nebulised Heparin combined with Pulmicort and N-acetylcysteine.
Group 2: Nebulised Pulmicort and N-acetylcysteine. Comparing on the 1st, 3rd and 7th days after aerosol.
Results: The results showed that the compliance of the Heparin aerosolized group was statistically significantly higher than that of nebulizer without Heparin (p < 0.05). On the 3rd day after mechanical ventilation, the PaO2/FiO2 ratio was higher and the lung injury score was significantly lower in the heparin nebulized group (p < 0.05). There was no difference in lung injury in the Heparin nebulized group (p > 0.05), while in the non-Heparin nebulizer group significantly increased (p < 0.05). The platelet value difference was not statistically significant before and after treatment in both groups (p > 0.05).
Conclusions: Nebulization with Heparin combined with Pulmicort and N-acetylcysteine significantly improved compliance, did not change the lung injury score.

Article Details

Keywords

Burn, inhalation injury, Heparin

References

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