Báo cáo một trường hợp ghép da đồng loại từ người hiến tạng chết não tại Bệnh viện Chợ Rẫy

Abstract

Objective: Fire burns of large areas and depths caused by gasoline and gas at the Burn and Plastic Surgery Department of Cho Ray Hospital are still very common today. To save the patient's life, it is necessary to remove necrosis and cover the wound early to minimize infection, loss of water, electrolytes, and proteins through the wound, reduce pain, speed up the healing process, and improve survival. Survival rate for patients. Skin grafting from relatives has been applied at the Department many years ago to treat patients. We would like to present the first case of allogeneic skin grafting from a brain-dead donor at the Department.
Methods: After intensive resuscitation, burn patients received early wound debridement twice, allograft skin from a brain-dead donor once, and then autologous skin grafts twice.
Results: The allograft skin adhered well. After 10 days, there was a gradual peeling phenomenon due to graft rejection, revealing a beautiful granulation tissue base. The patient received two more autologous skin grafts, the grafted skin adhered well, the wound healed completely, and was discharged from the hospital.
Conclusion: Skin allograft has been used in clinical practice for more than a century, and is the most physiological skin replacement material, helping to create a barrier against infection, loss of water, electrolytes, and proteins through the wound, reduces pain, is good for wound healing, and improves survival rates for patients. However, currently, the rate of organ and skin donors in our country in general is still low, and the Faculty does not have a tissue graft bank to preserve allograft skin.