Deep vein thrombosis at lower extremities in severe burn patient

Nguyen Thi Huong1,, Nguyen Hai An1, Ho Thi Van Anh1
1 Le Huu Trac National Burn Hospital

Main Article Content

Abstract

Deep vein thrombosis (DVT) involves the development of blood clots within the deep veins, typically occurring in the lower extremities...The mechanism of DVT formation is due to the combination of 3 factors (called Virchow's triangle): stasis, hypercoagulability, and endothelial injury. Severe burn patients often have all three components of Virchow's triad. Hypercoagulability from increased fibrinogen, coagulation factors level and platelet count; stasis from prolonged immobilization and multiple surgical procedures; endothelial injury from the systemic inflammatory response and mechanical trauma from central venous catheters [2, 4].
We report a case of a 51% total body surface area (TBSA) burn patient who developed deep vein thrombosis on day 52.

Article Details

References

1. AlHarbi, M., et al. (2021), "Pulmonary embolism in an anticoagulated burn patient: A case report", Saudi J Anaesth. 15(4), pp. 444-446.
2. Bordeanu-Diaconescu, E. M., et al. (2024), "Venous Thromboembolism in Burn Patients: A 5-Year Retrospective Study", Medicina (Kaunas). 60(2).
3. Fecher, A. M., et al. (2004), "Analysis of deep vein thrombosis in burn patients", Burns. 30(6), pp. 591-3.
4. Liu, A., et al. (2021), "Venous Thromboembolism Chemoprophylaxis in Burn Patients: A Literature Review and Single-Institution Experience", J Burn Care Res. 42(1), pp. 18-22.
5. Meizoso, J. P., et al. (2015), "Hypercoagulability and venous thromboembolism in burn patients", Semin Thromb Hemost. 41(1), pp. 43-8.
6. Mullins, F., et al. (2013), "Thromboembolic complications in burn patients and associated risk factors", J Burn Care Res. 34(3), pp. 355-60.
7. Peng, H., et al. (2020), "Risk Assessment of Deep Venous Thrombosis and It's Influencing Factors in Burn Patients", J Burn Care Res. 41(1), pp. 113-120.