Changes and relating factors to plasma albumin level among severely burn patients

Nguyen Nhu Lam1,, Phan Quoc Khanh2, Nguyen Hai An1
1 Le Huu Trac National Burn Hospital
2 4th Military Hospital/ 4th Military Region

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Abstract

The aims of this study were to determine changes and related factors to serum albumin levels among severely adult burn patients. The result indicated that serum albumin level prolongs reduced at the hospital admission and at later times and was still lower than the normal range on the 21st day after burn. An insignificant relationship was recorded between albumin level and gender, age.
Serum albumin concentrations were significantly lower in the group of burns ≥ 60% TBSA from day 7 after burn, full-thickness burn area ≥ 20% TBSA (on admission and 14th-day afterburn), or inhalation injury (14th-day post-burn). Serum albumin levels were also significantly lower in patients developed complication or died at almost time points (p < 0.05). However, the correlation was only from week to moderate (-0.29 to - 0.47). 

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References

1. Evans DC, Corkins MR, Malone A, Miller S, et al. The Use of Visceral Proteins as Nutrition Markers: An ASPEN Position Paper. Nutr Clin Pract. 2021; 36(1):22-28.
2. Ballmer PE. Causes and mechanisms of hypoalbuminemia, Clinical Nutrition. 2001; 23(3):271 - 273.
3. Dickson PW, Bannister D, Schreiber G. Minor burns lead to major changes in synthesis rates of plasma proteins in the liver. The Journal of trauma. 1987; 27(3):283-286.
4. Pérez-Guisado J, de Haro-Padilla JM, Rioja LF. et al. Serum albumin levels in burn people are associated to the total body surface burned and the length of hospital stay but not to the initiation of the oral/enteral nutrition. International journal of burns and trauma. 2013; 3(3):59.
5. Kim GH, Oh KH, Yoon JW, et al. Impact of burn size and initial serum albumin level on acute renal failure occurring in major burn. American journal of nephrology. 2003; 23(1):55-60.
6. Gong MN, Thompson BT, Williams P, et al. Clinical predictors of and mortality in acute respiratory distress syndrome: potential role of red cell transfusion. Critical care medicine. 2005; 33(6):1191-1198.
7. Gupta S, Bhattacharya S, Goyal P. The impact of first-day levels of serum proteins and lipids and their subsequent trends as prognostic indicators of burn mortality. Indian Journal of Burns. 2018; 26(1):48.
8. Gupta S, Bhattacharya S, Goyal P. Role of first day levels and subsequent trends of serum proteins in acute burns. J Acute Dis. 2018; 7(1):3135.
9. Aguayo-Becerra OA, Torres-Garibay C, Macías-Amezcua MD, et al. Serum albumin level as a risk factor for mortality in burn patients. Clinics. 29013; 68 (7): 940-945.