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The analgesic efficacy of Nefopam - Fentanyl mixture for patient-controlled analgesia post-knee arthroscopic surgery pain relief
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Abstract
Objective: To evaluate the analgesic efficacy of the nefopam-fentanyl mixture for patient-controlled analgesia after knee arthroscopic surgery.
Methodology: Clinical descriptive study, prospective on 50 patients undergoing arthroscopic knee surgery under spinal anesthesia, analgesic with a ratio mixture (fentanyl: 12.5 mcg/ml; nefopam: 1.5 mg/ml); PCA settings with the following parameters: background dose 1 ml/h (25 mcg/h), bolus dose 1 ml (25 mcg), lockout time 10 minutes, maximum dose 15 ml/4 hours. Evaluate postoperative pain relief effectiveness by VAS score at rest and during movement, postoperative pain medication consumption, and postoperative patients' satisfaction.
Results: At the 24 hours after surgery, the patient's VAS pain score at rest and during movement was 1.18 ± 1.11 (0 - 3) and 2.52 ± 1.21 (0 - 6); the average dosage of Fentanyl and Nefopam used was 27.78 ± 1.542ml (25ml - 30ml); the number of boluses of pain medication was 3.78 ± 1.54 times (1 - 6 times); there were no cases requiring rescue pain relief; all patients were very satisfied (56%) and satisfied (44.0%).
Conclusion: Postoperative pain relief after arthroscopic knee surgery with a mixture of nefopam and fentanyl solution administered intravenously by patients showed good pain relief.
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Keywords
Patient-controlled analgesia, Nefopam, Fentanyl, knee arthroscopic surgery
References
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