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Date Published: 30/04/2021
Online Published: 26/10/2021
Abstract Views: 157
Views Full article: 63
Issue
No. 2 (2021)
Section
Articles
How to Cite
Nguyen, N. S., Le, D. M., & Le, T. T. H. (2021). Survey the change in platelet count of severe burn patients. Journal of Disaster Medicine and Burn Injuries, 2, 36-41. https://jbdmp.vn/index.php/yhthvb/article/view/38

Survey the change in platelet count of severe burn patients

Nguyen Ngoc Son1,, Le Duc Man1, Le Thi Thu Huyen2
1 Le Huu Trac National Burn Hospital
2 108 Military Central Hospital

Main Article Content

Abstract

Aims: To evaluate the change in platelet count of severe burn patients.
Materials and methods: A prospective study on 37 severe burn patients who were admitted within 24 hours after burn injury from March 2020 to December 2020 in the ICU of the National Burn Hospital.
Results: Platelet count decreased lowest on day 3 after burn (96.32 ± 38.42G/l), gradually increased from 7th day and to normal limit on 14th and 21st post-burn day. The platelet count was statistically significantly different at the time of hospital admission. The proportion of patients with thrombocytopenia < 150 G/l accounted for the highest proportion on day 3 after burns (89.19%). At day 7 post-burn, platelets had infectious prognosis value with AUC = 0.712, sensitivity 58.3% and specificity 79.2% (p < 0.05).
The platelet count in the non-survivor group was lower and the difference was significant compared with the survivor group at the 7th post-burn day (p < 0.05). There was a strong negative relationship between platelet count and mortality on the 7th (r = -0,502), 14th (r = -0.511) and 21st (r = -0.617) post-burn day.
Conclusion: The platelet count decreased lowest at day 3 after the burn and lower in the mortality group. The platelet count at day 7 was significant with prognosis of infection with AUC = 0.712, a sensitivity of 58.3% and specificity 79.2% (p < 0.05). Platelet count was a negative significant relationship with mortality at 7th, 14th, and 21st post-burn days.

Article Details

Keywords

Platelet, severe burns

References

1. Marck R. E., Montagne H. L., Tuinebreijer W. E. et al. (2013). Time course of thrombocytes in burn patients and its predictive value for outcome. Burns, 39 (4), 714-722.
2. Cato L. D., Wearn C. M., Bishop J. R. et al. (2018). Platelet count: A predictor of sepsis and mortality in severe burns. Burns, 44 (2), 288-297.
3. Guo F., Wang X., Huan J. et al. (2012). Association of platelet counts decline and mortality in severely burnt patients. Journal of critical care, 27 (5), 529. e521-529. e527.
4. Gajbhiye A. S., Meshram M. và Kathod A. P. (2013). Platelet count as a prognostic indicator in burn septicemia. Indian Journal of Surgery, 75 (6), 444-448.
5. Andel D., Kamolz L.-P., Niedermayr M. et al. (2007). Which of the abbreviated burn severity index variables are having an impact on the hospital length of stay? Journal of burn care & research, 28 (1), 163-166.
6. Dellinger R. P., Levy M. M., Rhodes A. et al. (2013). Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive care medicine, 39 (2), 165-228.
7. Sepsis A. B. A. C. C. o. B., Group I., Greenhalgh D. G. et al. (2007). American Burn Association consensus conference to define sepsis and infection in burns. Journal of burn care & research, 28 (6), 776-790.
8. Vardon-Bounes F., Ruiz S., Gratacap M.-P. et al. (2019). Platelets are critical key players in sepsis. International journal of molecular sciences, 20 (14), 3494.
9. Pavić M. và Milevoj L. (2007). Platelet count monitoring in burn patients. Biochemia Medica: Biochemia Medica, 17 (2), 212-219.
10. Qiu L., Chen C., Li S.-J. et al. (2017). Prognostic values of red blood cell distribution width, platelet count, and red cell distribution width-to-platelet ratio for severe burn injury. Scientific Reports, 7 (1), 1-7.
11. Osuka A., Ishihara T., Shimizu K. et al. (2019). Natural kinetics of blood cells following major burn: Impact of early decreases in white blood cells and platelets as prognostic markers of mortality. Burns, 45 (8), 1901-1907.