Survey the change in platelet count of severe burn patients

Nguyen Ngoc Son1,, Le Duc Man1, Le Thi Thu Huyen2
1 Le Huu Trac National Burn Hospital
2 108 Military Central Hospital

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Abstract

Aims: To evaluate the change in platelet count of severe burn patients.
Materials and methods: A prospective study on 37 severe burn patients who were admitted within 24 hours after burn injury from March 2020 to December 2020 in the ICU of the National Burn Hospital.
Results: Platelet count decreased lowest on day 3 after burn (96.32 ± 38.42G/l), gradually increased from 7th day and to normal limit on 14th and 21st post-burn day. The platelet count was statistically significantly different at the time of hospital admission. The proportion of patients with thrombocytopenia < 150 G/l accounted for the highest proportion on day 3 after burns (89.19%). At day 7 post-burn, platelets had infectious prognosis value with AUC = 0.712, sensitivity 58.3% and specificity 79.2% (p < 0.05).
The platelet count in the non-survivor group was lower and the difference was significant compared with the survivor group at the 7th post-burn day (p < 0.05). There was a strong negative relationship between platelet count and mortality on the 7th (r = -0,502), 14th (r = -0.511) and 21st (r = -0.617) post-burn day.
Conclusion: The platelet count decreased lowest at day 3 after the burn and lower in the mortality group. The platelet count at day 7 was significant with prognosis of infection with AUC = 0.712, a sensitivity of 58.3% and specificity 79.2% (p < 0.05). Platelet count was a negative significant relationship with mortality at 7th, 14th, and 21st post-burn days.

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References

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