Characteristics of blood coagulation disorders in severe burn patients during the firt 3 days after burn

Tran Dinh Hung1,, Duong Van Phu1
1 Le Huu Trac National Burn Hospital

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Abstract

Objective: To investigate the status of blood coagulation disorders in severe burn patients during the 3 days after burn.
Patients and methods: Prospective study on 81 severe burn patients from 8/2023 to 5/2024 treated in ICU, Le Huu Trac National burn hospital. Coagulation parameter were tested at 2 time: T0 (time the admission) and T3 (day 3 after burn).
Research results: At T0, 18 patients had decreased platelets (< 150G/L) and increased PT (22.22%), 10 patients had decreased fibrinogen (12.35%) and 24 patients had increased fibrinogen (29.63%), 10 patients had prolonged APTT (24.69%).
At T3, 63 patients had decreased platelets (77.03%), 74 patients had increased fibrinogen (100%), 10 patients had prolonged APTT (13.51%). 100% of patients had D-dimer values > 500 µg/l. Among the 9 patients tested for ROTEM at T0, 33.33% of patients had coagulation disorders.
Conclusion: Coagulation disorder is a common condition in severe burn patients during the burn shock phase.

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References

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