Study on changes in serum sodium levels in patients with intracerebral hemorrhage and related factors
Main Article Content
Abstract
Objective: To describe the variations in serum sodium levels in patients with intracerebral hemorrhage (ICH) and to analyze associated factors.
Subjects and methods: A prospective longitudinal descriptive analytical study was conducted on 112 patients diagnosed with ICH and treated at the Intensive Care Unit of Military Hospital 175 from June 2023 to December 2024.
Results: This study evaluated sodium disturbances in 112 ICH patients. Hyponatremia was observed in 59 patients (52.7%), primarily of mild severity (52.6%). The main causes were syndrome of inappropriate antidiuretic hormone secretion (SIADH, 35.6%) and cerebral salt-wasting syndrome (CSWS, 25.4%), while 39% of cases had unidentified etiologies. Hyponatremia was significantly associated with hypertension (OR = 2.6, p = 0.036), smoking (OR = 2.4, p = 0.048), and large hematoma volume (> 60 cm³,
p = 0.028). Frontal lobe lesions showed a potential association with hyponatremia (OR = 3.1, p = 0.076).
Conclusion: Hyponatremia is common among patients with intracerebral hemorrhage and is associated with hypertension, smoking, and hematoma volume. SIADH and CSWS are the leading causes; however, further research is needed to clarify the cases with unknown etiology.
Article Details
Keywords
Intracerebral hemorrhage, Frontal lobe, Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
References
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