Preliminary evaluation of the therapeutic effectiveness of silicone pressure dressing (Gelzone) in the prevention of post-burn scarring
Main Article Content
Abstract
Objective: To conduct a preliminary evaluation of the effectiveness of silicone pressure dressing (Gelzone) in preventing post-burn scars.
Subjects and methods: A prospective descriptive, uncontrolled clinical trial was carried out on 30 patients with post-burn sequelae scars of the extremities who presented at the Center for Plastic and Reconstructive Surgery - Le Huu Trac National Burn Hospital, between August 2024 and August 2025.
Results: Most patients were female (66.7%), with a mean age of 29.2 ± 13.8 years. Thermal injury accounted for the majority of burn causes (86.7%). Scars were predominantly located in the lower extremities (76.7%), especially on the legs (56.7%). Hypertrophic scars were the most common type (73.3%), with 76.7% of patients experiencing both pain and pruritus. The mean VAS pain score significantly decreased from 6.8 ± 1.5 before treatment to 1.3 ± 1.4 at 6 months (p < 0.001). Vancouver Scar Scale parameters, including pigmentation, vascularity, pliability, and height, showed statistically significant improvement after treatment, particularly at 3 and 6 months (p < 0.001).
Conclusion: Gelzone silicone pressure dressing demonstrated promising effectiveness in improving pain and clinical characteristics of post-burn scars. This method appears to be safe and effective, warranting broader clinical application and further investigation.
Article Details
Keywords
Silicone pressure dressing, post-burn scars
References
2. Van Baar M.E. (2020). Epidemiology of Scars and Their Consequences: Burn Scars. Textbook on Scar Management: State of the Art Management and Emerging Technologies. Springer, Cham (CH).
3. Jiang Q., Chen J., Tian F., et al. (2021). Silicone gel sheeting for treating hypertrophic scars. Cochrane Database of Systematic Reviews, 2021(9).
4. Harris I.M., Lee K.C., Deeks J.J., et al. (2024). Pressure‐garment therapy for preventing hypertrophic scarring after burn injury. Cochrane Database Syst Rev, 2024(1), CD013530.
5. E. C. Huskisson (1974). Measurement of pain. The Lancet, 1127-1131.
6. Chae J.K., Kim J.H., Kim E.J., et al. (2016). Values of a Patient and Observer Scar Assessment Scale to Evaluate the Facial Skin Graft Scar. Ann Dermatol, 28(5), 615.
7. Li-Tsang C.W.P., Zheng Y.P., Lau J.C.M. (2010). A randomized clinical trial to study the effect of silicone gel dressing and pressure therapy on posttraumatic hypertrophic scars. J Burn Care Res, 31(3), 448-457.
8. Harte D., Gordon J., Shaw M., et al. (2009). The use of pressure and silicone in hypertrophic scar management in burns patients: a pilot randomized controlled trial. J Burn Care Res, 30(4), 632-642.
9. Wang F., Li X., Wang X., et al. (2020). Efficacy of topical silicone gel in scar management: A systematic review and meta‐analysis of randomised controlled trials. Int Wound J, 17(3), 765-773.
10. Ai JW., Liu J., Pei S.-D., et al. (2017). The effectiveness of pressure therapy (15-25 mmHg) for hypertrophic burn scars: A systematic review and meta-analysis. Sci Rep, 7(1), 40185.