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Date Published: 02/12/2025
Online Published: 02/12/2025
Abstract Views: 35
Views article details: 6
DOI: https://doi.org/10.54804/yhthvb.6.2025.529
Issue
No. 6 (2025)
Section
Articles
How to Cite
Nguyen, T. T., Nguyen, T. T. N., Pham, T. H. Y., Nguyen, T. T., & Nguyen, T. V. (2025). Antimicrobial resistance profiles of Staphylococcus epidermidis septicemia in Vietnamese cancer patients. Journal of Disaster Medicine and Burn Injuries, 6, 53-59. https://doi.org/10.54804/yhthvb.6.2025.529

Antimicrobial resistance profiles of Staphylococcus epidermidis septicemia in Vietnamese cancer patients

Nguyen Thanh Tung1, Nguyen Thi Tuyet Nga2, Pham Thi Hai Yen2, Nguyen Thi Thuan2, Nguyen Thanh Viet2,
1 Tan Trieu National Cancer Hospital, Hanoi, Vietnam
2 Le Huu Trac National Burn Hospital

Main Article Content

Abstract

Staphylococcus epidermidis is an important cause of bloodstream infections and a cause of morbidity and mortality in cancer patients. The antimicrobial resistance profiles of S. epidermidis septicemia in Vietnamese cancer patients are limited. We surveyed all S. epidermidis blood culture isolates from Vietnamese cancer patients at the Tan Trieu National Cancer Hospital, from 2020 to 2024. A total of 11 S. epidermidis isolates were identified and antibiotic susceptibility testing was employed. Methicillin resistance was detected in 4/11 of all isolates; all were sensitive to vancomycin, nitrofurantoin, linezolid, quinupristin-dalfopristin; however, all were resistant to benzylpenicillin, oxacillin; 7/11 of isolates were resistant to clindamycin, erythromycin, and trimethoprim-sulfamethoxazole; All of the isolates (11/11) are multidrug resistance. Vancomycin, nitrofurantoin, linezolid, and quinupristin-dalfopristin are effective antimicrobial agents in treating S. epidermidis septicemia in Vietnamese cancer patients. The high level of methicillin and multidrug resistance limited the therapeutic options in Vietnamese cancer patients are causes of concern.

Article Details

Keywords

S. epidermidis, vancomycin, methicillin, septicemia, Vietnamese, cancer

References

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