Article Sidebar
Date Published:
02/12/2025
Online Published:
02/12/2025
Abstract Views: 37
Views article details: 4
Views article details: 4
Issue
Section
Articles
How to Cite
Tran, D. H., & Ngo, T. H. (2025). Successful treatment of a patient with 98% total body surface area burns complicated by acute respiratory distress syndrome and septic shock. Journal of Disaster Medicine and Burn Injuries, 6, 80-86. https://doi.org/10.54804/yhthvb.6.2025.532
Successful treatment of a patient with 98% total body surface area burns complicated by acute respiratory distress syndrome and septic shock
Main Article Content
Abstract
Septic shock and acute respiratory distress syndrome (ARDS) are common complications that significantly increase mortality in patients with severe burns. Advances in hemodynamic resuscitation, rational antibiotic therapy, continuous blood purification using adsorptive membranes, prone-position ventilation with low tidal volumes, and the combined use of aerosolized and intravenous antibiotics in the treatment of pneumonia caused by multidrug-resistant gram-negative bacteria have markedly improved survival outcomes in severe burn patients.
Article Details
Keywords
Severe burns, septic shock, ARDS
References
1. 1. Sharma B., Harish D., Singh V.P. et al. (2006) Septicemia as a cause of death in burns: an autopsy study. Burns, 32(5):545-549.
2. 2. Śmiechowicz J. (2022) The Rationale and Current Status of Endotoxin Adsorption in the Treatment of Septic Shock. Journal of Clinical Medicine, 11(3):619.
3. 3. Monard C., Rimmele T., Ronco C. (2019) Extracorporeal blood purification therapies for sepsis. Blood purification, 47:2-15.
4. 4. Wang G., He Y., Guo Q. et al. (2023) Continuous renal replacement therapy with the adsorptive oXiris filter may be associated with the lower 28-day mortality in sepsis: a systematic review and meta-analysis. Critical Care, 27(1):275.
5. 5. Siew L.Y., Lee Z.-Y., Yunos N.a.M. et al. (2024) Outcomes of extracorporeal blood purification with oXiris® membrane in critically ill patients: A systematic review and meta-analysis. 83:154844.
6. 6. Weltert L., Turani F., Falco M. et al. (2018) Rf68 renal replacement therapy with the oxiris filter decreases inflammatory mediators and improves cardiorenal function in septic patients: A propensity-matched analysys against traditional renal filtration. Journal of Cardiovascular Medicine, 19:e78.
7. 7. Zhai Y., Pan J., Zhang C. (2021) The application value of oXiris-endotoxin adsorption in sepsis. American Journal of Translational Research, 13(4):3839.
8. 8. Mariano F., Depetris N., Malvasio V. et al. (2020) Coupled-plasma filtration and adsorption for severe burn patients with septic shock and acute kidney injury treated with renal replacement therapy. Burns, 46(1):190-198.
9. 9. Lee H.G., Jang J., Choi J.E. et al. (2013) Blood stream infections in patients in the burn intensive care unit. Infection & chemotherapy, 45(2):194-201.
10. 10. Li L., Dai J.-x., Xu L. et al. (2018) Antimicrobial resistance and pathogen distribution in hospitalized burn patients: a multicenter study in Southeast China. Medicine, 97(34).
11. 11. Ngô Tuấn Hưng, Nguyễn Hải An, Trần Đình Hùng et al. (2017) Đánh giá hiệu quả của lọc máu liên tục trong điều trị sốc nhiễm khuẩn trên bệnh nhân bỏng nặng. Tạp chí y học thảm họa và bỏng, 4:60-65.
12. 12. Ngô Tuấn Hưng, Nguyễn Hải An, Trần Đình Hùng et al. (2019) Hiệu quả của liệu pháp điều trị sốc nhiễm khuẩn theo mục tiêu sớm trên bệnh nhân bỏng nặng tại Khoa hồi sức cấp cứu, Bệnh Viện Bỏng Quốc gia. Tạp chí y học thảm họa và bỏng, 2:35 - 43.
13. 13. Cartotto R., Ellis S., Smith T. (2005) Use of high-frequency oscillatory ventilation in burn patients. Critical care medicine, 33(3):S175-S181.
14. 14. Cartotto R., Cooper A.B., Esmond J.R. et al. (2001) Early clinical experience with high-frequency oscillatory ventilation for ARDS in adult burn patients. The Journal of burn care & rehabilitation, 22(5):325-333.
15. 15. Fan E., Del Sorbo L., Goligher E.C. et al. (2017) An official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine clinical practice guideline: mechanical ventilation in adult patients with acute respiratory distress syndrome. American journal of respiratory and critical care medicine, 195(9):1253-1263.
16. 16. Grasselli G., Calfee C.S., Camporota L. et al. (2023) ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies. 49(7):727-759.
17. 17. Koulouras V., Papathanakos G., Papathanasiou A. et al. (2016) Efficacy of prone position in acute respiratory distress syndrome patients: a pathophysiology-based review. World journal of critical care medicine, 5(2):121.
18. 18. Almangour T.A., Alruwaili A., Almutairi R. et al. (2021) Aerosolized plus intravenous colistin vs intravenous colistin alone for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria: A retrospective cohort study. International Journal of Infectious Diseases, 108:406-412.
19. 19. Karaiskos I., Gkoufa A., Polyzou E. et al. (2023) High-dose nebulized colistin methanesulfonate and the role in hospital-acquired pneumonia caused by gram-negative bacteria with difficult-to-treat resistance: a review. Microorganisms, 11(6):1459.
2. 2. Śmiechowicz J. (2022) The Rationale and Current Status of Endotoxin Adsorption in the Treatment of Septic Shock. Journal of Clinical Medicine, 11(3):619.
3. 3. Monard C., Rimmele T., Ronco C. (2019) Extracorporeal blood purification therapies for sepsis. Blood purification, 47:2-15.
4. 4. Wang G., He Y., Guo Q. et al. (2023) Continuous renal replacement therapy with the adsorptive oXiris filter may be associated with the lower 28-day mortality in sepsis: a systematic review and meta-analysis. Critical Care, 27(1):275.
5. 5. Siew L.Y., Lee Z.-Y., Yunos N.a.M. et al. (2024) Outcomes of extracorporeal blood purification with oXiris® membrane in critically ill patients: A systematic review and meta-analysis. 83:154844.
6. 6. Weltert L., Turani F., Falco M. et al. (2018) Rf68 renal replacement therapy with the oxiris filter decreases inflammatory mediators and improves cardiorenal function in septic patients: A propensity-matched analysys against traditional renal filtration. Journal of Cardiovascular Medicine, 19:e78.
7. 7. Zhai Y., Pan J., Zhang C. (2021) The application value of oXiris-endotoxin adsorption in sepsis. American Journal of Translational Research, 13(4):3839.
8. 8. Mariano F., Depetris N., Malvasio V. et al. (2020) Coupled-plasma filtration and adsorption for severe burn patients with septic shock and acute kidney injury treated with renal replacement therapy. Burns, 46(1):190-198.
9. 9. Lee H.G., Jang J., Choi J.E. et al. (2013) Blood stream infections in patients in the burn intensive care unit. Infection & chemotherapy, 45(2):194-201.
10. 10. Li L., Dai J.-x., Xu L. et al. (2018) Antimicrobial resistance and pathogen distribution in hospitalized burn patients: a multicenter study in Southeast China. Medicine, 97(34).
11. 11. Ngô Tuấn Hưng, Nguyễn Hải An, Trần Đình Hùng et al. (2017) Đánh giá hiệu quả của lọc máu liên tục trong điều trị sốc nhiễm khuẩn trên bệnh nhân bỏng nặng. Tạp chí y học thảm họa và bỏng, 4:60-65.
12. 12. Ngô Tuấn Hưng, Nguyễn Hải An, Trần Đình Hùng et al. (2019) Hiệu quả của liệu pháp điều trị sốc nhiễm khuẩn theo mục tiêu sớm trên bệnh nhân bỏng nặng tại Khoa hồi sức cấp cứu, Bệnh Viện Bỏng Quốc gia. Tạp chí y học thảm họa và bỏng, 2:35 - 43.
13. 13. Cartotto R., Ellis S., Smith T. (2005) Use of high-frequency oscillatory ventilation in burn patients. Critical care medicine, 33(3):S175-S181.
14. 14. Cartotto R., Cooper A.B., Esmond J.R. et al. (2001) Early clinical experience with high-frequency oscillatory ventilation for ARDS in adult burn patients. The Journal of burn care & rehabilitation, 22(5):325-333.
15. 15. Fan E., Del Sorbo L., Goligher E.C. et al. (2017) An official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine clinical practice guideline: mechanical ventilation in adult patients with acute respiratory distress syndrome. American journal of respiratory and critical care medicine, 195(9):1253-1263.
16. 16. Grasselli G., Calfee C.S., Camporota L. et al. (2023) ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies. 49(7):727-759.
17. 17. Koulouras V., Papathanakos G., Papathanasiou A. et al. (2016) Efficacy of prone position in acute respiratory distress syndrome patients: a pathophysiology-based review. World journal of critical care medicine, 5(2):121.
18. 18. Almangour T.A., Alruwaili A., Almutairi R. et al. (2021) Aerosolized plus intravenous colistin vs intravenous colistin alone for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria: A retrospective cohort study. International Journal of Infectious Diseases, 108:406-412.
19. 19. Karaiskos I., Gkoufa A., Polyzou E. et al. (2023) High-dose nebulized colistin methanesulfonate and the role in hospital-acquired pneumonia caused by gram-negative bacteria with difficult-to-treat resistance: a review. Microorganisms, 11(6):1459.