Assessment of the therapeutic efficacy of an advanced physical antimicrobial dressing in the management of partial-thickness burns
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Abstract
Background: Partial-thickness burns are common, painful, and prone to infection. The Sorbact-DACC dressing with a bacterial-binding mechanism dressing may improve outcomes. This study evaluates its initial results.
Subjects and methods: A prospective descriptive longitudinal study was conducted in 30 patients (18 - 65 years) with partial-thickness burns (grade II and superficial grade III according to Le The Trung), total burn surface area ≤ 50%, admitted to the Intensive Care Unit (01 - 03/2025). Cutimed Sorbact dressing was applied, changed every 2 days. Pain (VAS) and wound cultures were assessed at N1, N3, N7, N14. Data were analyzed using Stata 17.0; p < 0.05 was considered statistically significant.
Results: Bacterial load among culture-positive sample increased at N3 (38.2 ± 15.5×10³ CFU/cm²) then decreased at N7 (2.3 ± 0.8) and N14 (1.5 ± 0.2) (p < 0.001). Negative culture rates were 53.3% at N7 and 70% at N14 (p < 0.05). Mean epithelialization time was 11.8 ± 3.2 days; dressing changes 4.5 ± 1.8. VAS score decreased from 7.1 ± 1.2 to 1.8 ± 0.8 (p < 0.001).
Conclusions: The Sorbact-DACC dressing showed positive initial results in controlling bacterial load, promoting wound healing, and reducing pain in partial-thickness burns. Larger controlled studies are needed.
Article Details
Keywords
Partial-thickness burns, bacterial-binding mechanism, DACC, wound healing
References
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