Clinical characteristics of lower-limb wounds in patients with diabetes mellitus at the Wound Healing Center, Vietnam National Burn Hospital
Main Article Content
Abstract
Objective: To identify selected clinical characteristics of acute lower-extremity wounds in patients with diabetes mellitus type 2 and investigate risk factors associated with delayed wound healing.
Subjects and Methods: A prospective descriptive longitudinal study was conducted in total of 82 patients aged ≥ 30 years with diabetes mellitus type 2 and acute lower-extremity wounds, referred from other healthcare facilities and admitted to the Wound Healing Center, Le Huu Trac National Burn Hospital, within 24 hours, were included in the study from June 2025 to November 2025. Factors associated with wound status were evaluated.
Results: Among the study participants, 60.98% were over 50 years of age. Accidental injuries accounted for 51.22% of acute wounds. Hypertension was the most common comorbidity, occurring in 23.17% of patients. The duration of diabetes was less than 10 years in 67.07% of cases. The most common location of lower-extremity wounds was the foot and toes (58.54%). Moderate-depth wounds accounted for 76.83% of cases. An ankle-brachial index (ABI): 1-1,4 was observed in 73.17% of patients, while 6.1% required vascular intervention before continuing wound treatment.
Conclusion: Acute lower-extremity wounds in patients with diabetes mellitus are mainly caused by accidents, with the foot being the most commonly affected site. Assessment of the ABI and thorough evaluation of lower-extremity arterial status, together with timely vascular intervention, may contribute to more effective wound management.
Keywords
Diabetes mellitus, lower-extremity wounds, peripheral arterial disease (PAD)
Article Details
References
2. Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, Duncan BB, et al. IDF Diabetes Atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract. 2022;183:109119. doi:10.1016/j.diabres.2021.109119.
3. Burgess JL, Wyant WA, Abdo Abujamra B, Kirsner RS, Jozic I. Diabetic wound-healing science. Medicina (Kaunas) 2021, 57(10), 1072. doi: 10.3390/medicina57101072.
4. Bodman M, Friedman S, Clifford LB. Bullosis diabeticorum. A report of two cases with a review of the literature. J Am Podiatr Med Assoc. 1991;81:561-563
5. Jain AKC, Nisha ST, Vishwanath S. Carbuncle in diabetics-our experience. Scholars J Appl Med Sci. 2019;1:493-495
6. Singer AJ, Tassiopoulos A, Kirsner RS. Evaluation and management of lower-extremity ulcers, N Engl J Med. 2017;377(16): 1559-1567. Doi:10.1056/NEJMra1615243.
7. Nurzaman YA, Setiawan PR, Kasnadi MS. Cellulitis with ulcer on diabetes mellitus : a case report. Med Clin Updat J. 2023;2:8-11
8. Suriadi. An appearance characteristic ulcer in diabetic patients at Kitamura Clinic in Pontianak, Indonesia. Eur J Mol Clin Med. 2020;7:3436-3444
9. Athavale A, Fukaya E, Leeper NJ. Peripheral Artery Disease: Molecular Mechanisms and Novel Therapies. Arterioscler Thromb Vasc Biol. 2024. 44(6):1165-1170. Doi:10.1161/ATVBAHA.124.320195.