Influences of Propranolol on outcomes of severely adult burn patients.

Phan Quoc Khanh1, Nguyen Hai An2, Nguyen Nhu Lam3,
1 Military Medical Hospital 4/Military Region 4
2 Le Huu Trac National Burn Hospital
3 2Le Huu Trac National Burn Hospital

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Abstract

This study evaluated the influence of Propranolol on outcomes of severely adult burn patients. A randomized controlled trial was on 124 patients who were divided into two groups: Control group (A) received conventional treatment, study group (B) was treated with Propranolol.
The result indicated that, along the time, the heart rate of the study group steadily decreased and was significantly lower than that of the control group (90.24 ± 11.51 vs. 101.43 ± 13.69 bpm; p < 0,01 at 28th-day afterburn). From the 7th day onward afterburn, the body temperature of both groups decreased and the temperature was significantly lower than that in the control group (p < 0.05). Hematological parameters, mean arterial pressure, complication rate and treatment time were not remarkably different between the two groups (p > 0.05). There was also no significant difference in mortality between groups (19.35% vs 17.74%; p > 0.05).

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References

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