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Application of superficial radiation therapy combined with thin split-thickness skin grafting in treatment of extensive keloids on extremities post-burn
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Abstract
Introduction: Current treatment methods for extensive post-burn keloids exhibit high recurrence rates approaching 100%, along with the formation of keloids at donor sites, posing significant physical and psychological burdens on patients. At present, globally and in Vietnam, there remains no widely accepted and effective solution to manage extensive keloids on extremities post-burn, leaving patients with high risks of functional impairment.
Patients and methods: The research investigates the application of superficial radiation therapy (SRT-100) in combination with thin split-thickness skin grafting for patients with extensive keloids located on the extremities post-burn. The surgical procedures involved complete excision of keloid tissue followed by thin split-thickness skin grafting, coupled with subsequent superficial radiation to inhibit keloid recurrence, minimize surface tension, and prevent new keloid formation at donor sites or adjacent skin areas.
Results: Patients presented with extensive keloids averaging dimensions of approximately 15 x 8 cm, characterized by thick, stiff, and poorly mobile scar tissue associated with limited joint motion and chronic itching. Outcomes assessed over six months post-operatively revealed significant improvement in both functional recovery and cosmetic appearance: All patients (6/6 cases) exhibited restoration of normal limb function, and the cosmetic outcomes were assessed as good, showing 75% improvement compared to pre-treatment conditions.
Conclusion: The combined method of superficial radiation therapy and thin split-thickness skin grafting represents a viable and effective approach for overcoming current therapeutic challenges associated with extensive keloids on extremities.
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Keywords
Extensive keloids on extremities, distant expanded flaps, split-thickness skin grafting, superficial radiotherapy (SRT-100).
References
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