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Date Published: 20/09/2022
Online Published: 20/09/2022
Abstract Views: 388
Views Full article: 416
DOI: https://doi.org/10.54804/yhthvb.3.2022.146
Issue
No. 3 (2022)
Section
Articles
How to Cite
Nguyen, T. D., & Nguyen, N. T. (2022). Studying the Effects of Autologous Platelet Rich Plasma (PRP) on Changes of Immunohistochemistry Staining Speciment of Chronic Wound Local. Journal of Disaster Medicine and Burn Injuries, 3, 74-81. https://doi.org/10.54804/yhthvb.3.2022.146

Studying the Effects of Autologous Platelet Rich Plasma (PRP) on Changes of Immunohistochemistry Staining Speciment of Chronic Wound Local.

Nguyen Tien Dung1,, Nguyen Ngoc Tuan1
1 Le Huu Trac National Burn Hospital

Main Article Content

Abstract

Objective: This study was to evaluate the effects of Autologous Platelet Rich Plasma (PRP) on changes in immunohistochemistry staining specimens of chronic wound local.
Subjects and method: We conducted a descriptive longitudinal study at the Wound Healing Center of Vietnam National Burn Hospital, from November 2020 to May 2020. 30 patients with chronic wounds were enrolled in the study and were injected with the autologous PRP (PRP) in peri-wound and wound beds. We assessed and recorded the changes in immunohistochemistry staining specimens of chronic wound local at the time before therapy and the first, second and third week of studied progress.
Results: PRP helped to improve the wound healing process: Reduced the swelling and improve the structure of extracellular matrix (ECM) at chronic wound local (increased number of fibroblast cells and neo-vascular).
Conclusion: We realized that the autologous PRP promoted the wound healing process by improvement of ECM in the chronic wound site.

Article Details

Keywords

Chronic wound, autologous PRP, , immunohistochemistry

References

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