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Prevalence and degree of organ dysfunction at the time of diagnosis of septic shock in severe burn patients
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Abstract
Objective: Determine the prevalence and degree of organ dysfunction at the time of diagnosis of septic shock in severe burn patients.
Patients and method: A descriptive, cross-sectional study on 55 episodes of septic shock in 38 severe burns adult patients (16 - 60 years), treated at the Department of Emergency Resuscitation, Le Huu Trac National Burn Hospital from January 2023 to June 2024.
Results: In all septic shock episodes, patients had neurological and circulatory dysfunction according to the SOFA scale. In which, the majority of septic shock episodes had a SOFA = 2 for neurological organs (85.45%), and SOFA = 1 for circulatory organs (92.73%). Most septic shock episodes had respiratory dysfunction according to the SOFA score (74.54%), in which SOFA score ≥ 2 in 52.73% of septic shock episodes. Renal, hepatic, and hematological organ disorders according to SOFA score appeared in 27.27%, 21.82%, and 18.18%, respectively, during septic shock episodes. The SOFA score = 3 in liver and hematology appeared in only 1 episode of septic shock (1.82%), in kidney it was seen in 3 episodes of septic shock (5.45%).
The total SOFA score has a median of 5 points (4 - 6 points). Plasma TNF- and IL-6 concentrations were positively and moderately correlated with SOFA total score (p < 0.05).
Conclusion: At the time of diagnosis of septic shock in severe burn patients, there were mainly additional dysfunction of the nervous and respiratory organs.
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Keywords
Burn, SOFA score, Multiorgan Dysfunction Syndrome (MODS)
References
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