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Date Published: 28/10/2025
Online Published: 28/10/2025
Abstract Views: 108
Views article details: 21
DOI: https://doi.org/10.54804/yhthvb.5.2025.495
Issue
No. 5 (2025)
Section
Articles
How to Cite
Trinh, V. T., Nguyen, N. S., Nguyen, V. T., Dinh, X. C., & Hoang, V. C. (2025). Amputation and relation factors in diabetic foot ulcer patients treated at Nghe An General Friendship Hospital. Journal of Disaster Medicine and Burn Injuries, 5, 82-93. https://doi.org/10.54804/yhthvb.5.2025.495

Amputation and relation factors in diabetic foot ulcer patients treated at Nghe An General Friendship Hospital

Trinh Van Thong1,, Nguyen Ngoc Son1, Nguyen Viet Thanh1, Dinh Xuan Chuong1, Hoang Van Chau1
1 Nghe An General Friendship Hospital

Main Article Content

Abstract

Aims: To determine the risk factors for limb amputation in patients with diabetic foot ulcers at Nghe An Friendship General Hospital.
Patients and methods: This retrospective study enrolled 115 adult patients with diabetic foot ulcers admitted to Nghe An Friendship General Hospital between January 1, 2024, and June 30, 2025.
A purulent discharge specimen was collected from the ulcer before wound cleansing for bacterial culture. The primary outcome was the limb amputation rate. Cox regression analysis was utilized to estimate hazard ratios, and the time from study initiation to healing was evaluated as a censored time-to-event outcome using the Kaplan-Meier curve.
Results: A total of 115 patients with diabetic foot ulcers treated at Nghe An Friendship General Hospital were included, comprising 64 males (55.65%), with a mean age of 44.4 ± 14.7 years. In total, 34 (29.57%) diabetic foot ulcer patients were overweight, and 16 (13.91%) were obese, with a mean body mass index (BMI) of 24.94 ± 3.69 kg/m². A total of 56 (48.69%) diabetic foot ulcer patients presented with diabetic complications.
Among the diabetic foot ulcer patients, 35 (30.43%) underwent lower-extremity amputation (LEA). In total, 18 (46.15%) patients treated with inappropriate antibiotics achieved healing, while 21 (53.85%) patients did not heal (p = 0.017). Additionally, a higher Wagner grade was associated with poorer healing outcomes. A total of 19 (21.84%) patients with a Wagner grade of < 4 and 16 (57.14%) patients with a grade of ≥ 4 did not achieve healing (p = 0.005).
Conclusion: The rate of limb amputation among patients with diabetic foot ulcers was higher in those who received inappropriate antibiotic therapy and in those with severe-grade ulcers.

Article Details

Keywords

Diabetic foot, foot ulcer, foot amputation, risk factors

References

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