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Date Published: 30/06/2021
Online Published: 28/09/2021
Abstract Views: 440
Views Full article: 662
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No. 3 (2021)
Section
Articles
How to Cite
Nguyen, D. A., Nguyen, N. T., Tran, D. T., & Pham, T. T. H. (2021). The effectiveness on prevention from nausea, vomiting and adverse effects of Granisetron after thyroid surgery. Journal of Disaster Medicine and Burn Injuries, 3, 34-41. https://jbdmp.vn/index.php/yhthvb/article/view/5

The effectiveness on prevention from nausea, vomiting and adverse effects of Granisetron after thyroid surgery

Nguyen Duc Anh1,, Nguyen Ngoc Thach2, Tran Dac Tiep2, Pham Thi Thanh Huyen3
1 Học viện Quân y
2 Bệnh viện Quân y 103
3 Bệnh viện Bạch Mai

Main Article Content

Abstract

Objectives: To evaluate the effectiveness of prevention from nausea and vomiting, adverse effects of Granisetron after thyroid surgery.
Subjects and methods: 80 cases aged 16 and over with American Society of Anaesthesiologists physical status class I or II having indications for thyroid surgery under endotracheal anesthesia were divided into two groups with 40 cases for each group Immediately before premedication, patients of each group were intravenously injected with Granisetron 1mg (group G) or Ondansetron 4mg (group O).
Results: The percentages of nausea and vomiting from 6 to 8 hours (0%), from 0 to 24 hours after surgery (5%) in group G were lower than that in group O (15% and 22.5%), respectively. The difference was statistically significant with p < 0.05. The percentages of headache, dizziness, dry mouth, constipation were 10%, 12.5%, 7.5%, 7.5%, respectively in the group G and 15%, 15%, 10%, 17.5%, respectively in group O. The difference was not statistically significant with p > 0.05.
Conclusion: Intravenous injection Granisetron had effectiveness on prevention from nausea and vomiting after thyroid surgery with low, mild, transient adverse effects.

Article Details

Keywords

Nausea and vomiting, thyroid surgery, Granisetron

References

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