Tình trạng dinh dưỡng và thành phần cơ thể ở bệnh nhân loét Marjolin: Nghiên cứu cắt ngang trên 32 trường hợp

Abstract

Objective: To describe nutritional status, body composition, and associations between malnutrition and disease characteristics in patients with Marjolin’s ulcer.
Subjects and methods: A cross-sectional study was conducted on 32 patients with histologically confirmed Marjolin’s ulcer at the Le Huu Trac National Burn Hospital and Military Hospital 175 from January 2022 to December 2025. Nutritional risk was screened using NRS-2002, malnutrition was diagnosed according to GLIM criteria, and body composition was assessed using TANITA.
Results: Mean age was 54.7 ± 11.8 years; 84.4% of lesions developed from burn scars. Mean BMI was 20.5 ± 2.8 kg/m², and 28.1% were underweight. Men had higher muscle mass, whereas women had higher body fat percentage and fat mass (p <0.05). Nutritional risk according to NRS-2002 was present in 43.8%; malnutrition according to GLIM was present in 40.6%, including 28.1% moderate and 12.5% severe malnutrition. Malnourished patients had lower albumin, hemoglobin, lymphocyte count, and PNI, but higher CRP (p <0.05). In univariable analysis, malnutrition was associated with maximum lesion diameter ≥5 cm, lesion area ≥50 cm², and local infection (p <0.05).
Conclusion: Nutritional risk and malnutrition were common in patients with Marjolin’s ulcer. Nutritional screening and assessment should be performed before treatment.