Treatment outcomes in patients with diabetic ketoacidosis treated at Military Hospital 175
Main Article Content
Abstract
Objective: To describe the clinical and laboratory characteristics, treatment outcomes, and factors associated with treatment outcomes in patients with diabetic ketoacidosis (DKA) treated at Military Hospital 175.
Subjects and methods: A prospective descriptive study was conducted on 48 patients with diabetic ketoacidosis who were treated at Military Hospital 175 between February 2024 and October 2025.
Results: The study included 48 patients with diabetic ketoacidosis (DKA), with a mean age of 46.2 ± 15.1 years; 64.6% were female. Type 2 diabetes mellitus accounted for 68.8% of cases, and 54.2% of patients were newly diagnosed with diabetes. Infection was the most common precipitating factor (62.5%). Moderate DKA was the predominant severity category (58.3%). The DKA resolution rate was 91.7%, with a mean time to DKA resolution of 32.4 ± 12.3 hours. The mean length of hospital stay was 8.9 ± 4.1 days, and the survival-to-discharge rate was 95.8%. Hypoglycemia (29.2%) and hypokalemia (25.0%) were the most common treatment-related complications. Age ≥ 65 years, severe DKA, and impaired consciousness at admission were significantly associated with unfavorable treatment outcomes (p < 0.05).
Conclusion: Most patients with DKA responded favorably to treatment. Older age, severe DKA, and impaired consciousness at admission were associated with unfavorable treatment outcomes.
Keywords
Diabetes mellitus, Diabetic ketoacidosis, Risk factors
Article Details
References
2. Alvarez P.R., Martin V.T.S., và Morey-Vargas O.L. Hyperglycemic crises in adults: A look at the 2024 consensus report. CCJM. 2025. 92(3): 152-158. DOI: 10.3949/ccjm.92a.24089.
3. Lưu Ngọc Trân, Nguyễn Tường Vi, Thái Bình An và cộng sự. Nghiên cứu tỷ lệ và kết quả điều trị nhiễm toan ceton ở bệnh nhân đái tháo đường tại Bệnh viện Đa khoa thành phố Cần Thơ năm 2023, Tạp chí Y học Việt Nam. 2024. 544(1): 208-212. DOI: 10.51298/vmj.v544i1.11733.
4. Nguyễn Khổng Nhã Khoa, Phan Hữu Hên, Hoàng Trùng Dương. Kết quả điều trị nhiễm toan ceton do đái tháo đường típ 2 tại Bệnh viện Đa khoa Trung ương Cần Thơ, Tạp chí Y học Cộng đồng. 2026. 67(5): 162-166. DOI: 10.52163/yhc.v67i5.5156.
5. Nguyễn Minh Tuấn Anh, Nguyễn Khoa Diệu Vân. Mô tả đặc điểm lâm sàng và cận lâm sàng ở bệnh nhân đái tháo đường có biến chứng cấp tính (nhiễm toan ceton và/hoặc tăng áp lực thẩm thấu), Tạp chí Y học Việt Nam. 2023. 533(1): 161-165. DOI: 10.51298/vmj.v533i1.7734.
6. Jahoor, Farook; Hsu, Jean W; Mehta, Paras B; et al., "Metabolomics Profiling of Patients with A-β+ Ketosis-Prone Diabetes During Diabetic Ketoacidosis". Diabetes. 2021. 70:1898-1909 https://doi.org/10.2337/db21-00666.
7. Atiase Y., Yorke E., Akpalu J. et al. Clinical characteristics and severity of diabetic ketoacidosis: A cross-sectional study from a tertiary hospital in Ghana. Trop Med Int Health. 2023. 28(9): 790-796. DOI: 10.1111/tmi.13919.
8. Balmier A., Dib F., Serret-Larmande A. et al. Initial management of diabetic ketoacidosis and prognosis according to diabetes type: A French multicentre observational retrospective study. Annals of Intensive Care. 2019;9(1): 91. DOI: 10.1186/s13613-019-0567-y.
9. Lian Z.Y., Lee J.S.-Y., Rahmatullah I.H. et al. Metabolic Complications During the Initial Management of Diabetic Ketoacidosis According to Diabetes Típ in a Single Tertiary Centre in Malaysia. Cureus. 2026. 18(1): e101129. doi: 10.7759/cureus.101129.