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Issue: No. 3 (2026)
Section: Articles
Date Published: 28/10/2026
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How to Cite
Tran, D. H., & Ngo, T. H. (2026). Association between packed red blood cell transfusion and clinical outcomes in patients with severe burns. Journal of Disaster Medicine and Burn Injuries, 3. https://jbdmp.vn/index.php/yhthvb/article/view/569

Association between packed red blood cell transfusion and clinical outcomes in patients with severe burns

Tran Dinh Hung1,2, Ngo Tuan Hung1,2,
1 Le Huu Trac National Burn Hospital
2 Vietnam Military Medical University

Main Article Content

Abstract

Objective: To evaluate the association between packed red blood cell transfusion and clinical outcomes in patients with severe burns.
Methods: A retrospective descriptive study was conducted on 627 patients with severe burns who were treated in the Department of Emergency and Intensive Care, Vietnam National Burn Hospital, from January 2021 to December 2025.
Results: The overall mortality rate was 24.88%. The total volume of blood products transfused during hospitalization was 1.02 (0.57–1.63) mL/kg/%burn extent. Age, burn extent, deep burn area, inhalation injury, and the volume of blood products transfused per kg body weight per %burn extent were independently associated with mortality (all p < 0.01). The volume of blood products transfused per kg body weight per %burn extent demonstrated fair prognostic performance for mortality (AUC = 0.70), with a sensitivity of 64.74%, specificity of 64.33%, and an optimal cut-off value of 1.16 mL/kg/%burn exent. Survival probability was significantly lower in patients receiving >1.16 mL/kg/% burn exent of blood products compared with those receiving ≤1.16 mL/kg/% burn exent (χ² = 18.48, p < 0.001). Among survivors, the volume of blood products transfused per kg body weight per % burn exent was independently associated with length of hospital stay (β = 4.58, p < 0.001).
Conclusions: The volume of blood products transfused per kg body weight per % burn exent is independently associated with mortality and length of hospital stay among survivors with severe burns.

Keywords

severe burns, blood transfusion, mortality

Article Details

References

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