Preliminary evaluation of Anson nano silver dressing on partial-thickness burn wounds
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Abstract
Objective: To evaluate local clinical progression and antibacterial effects of Anson nano silver dressing compared to 1% silver sulfadiazine cream (SSD 1%) on partial-thickness burn wounds.
Methods: A prospective, interventional, self-controlled study was conducted on 30 patients with thermal burns of degree II and III at National Burn Hospital Le Huu Trac from January to April 2025. Each patient had two comparable wound areas: area A treated with Anson nano silver dressing, area B with SSD 1%. Assessment included edema, exudate, time to edema resolution, wound healing time, number of dressing changes, and bacterial density at baseline (day 0) and after 7 days (day 7).
Results: At day 7, 14/16 (87.5%) of area A had minimal or no edema compared to 2/22 (9.1%) of area B (p < 0.05). Time to edema resolution was shorter in area A for degree II (4.01 ± 0.65 vs. 4.89 ± 2.43 days; p < 0.01) and degree III (5.64 ± 0.78 vs. 7.06 ± 1.90 days; p < 0.01). Healing time was shorter in area A for both degree II (6.1 ± 0.6 vs. 8.1 ± 0.9 days; p < 0.05) and degree III (14.3 ± 0.4 vs. 15.4 ± 0.7 days; p < 0.05). Dressing changes were significantly reduced in both degrees (degree II: 2.7 ± 0.1 vs. 12.0 ± 2.2; degree III: 12.1 ± 0.1 vs. 15.1 ± 1.1; p < 0.05). Bacterial density decreased significantly in both areas after 7 days (p < 0.05) with no statistically significant difference between the two therapies at the same time point (p > 0.05).
Conclusion: Within the scope of this study, Anson nano silver dressing showed effects on edema, exudate, number of dressing changes, and wound healing time compared to SSD 1%. No statistically significant difference in bacterial density was detected between the two methods at day 7. Further studies with larger sample sizes are needed to confirm these results.
Keywords
Burn, nano silver, silver sulfadiazine, wound healing, infection
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References
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