Article Sidebar

Full article
Date Published: 25/03/2022
Online Published: 25/03/2022
Abstract Views: 405
Views Full article: 163
DOI: https://doi.org/10.54804/yhthvb.1.2022.97
Issue
No. 1 (2022)
Section
Articles
How to Cite
Tran, D. H., & Nguyen, N. L. (2022). Research risk factors affecting treatment outcomes of severe burn patients with ARDS complications. Journal of Disaster Medicine and Burn Injuries, 1, 18-25. https://doi.org/10.54804/yhthvb.1.2022.97

Research risk factors affecting treatment outcomes of severe burn patients with ARDS complications

Tran Dinh Hung1,, Nguyen Nhu Lam1
1 Le Huu Trac National Burn Hospital

Main Article Content

Abstract

Aims: Our study aims to explore the risk factors affecting treatment outcomes of severe burn patients with ARDS complications.
Materials and methods: A prospective study was conducted on 66 patients with ARDS, treated in ICU, National Institute of Burns from 2014 to 2017. The criteria were defined according to the Berlin Definition. Logistic regression analysis was applied to screen clinically accessible risk factors for survival. 
Results: The total mortality in ARDS patients was 62.12%. Logistic regression analysis showed that: Lactate level (p = 0.024, OR = 6.7089), platelet count (p = 0.04, OR = 0.9927), lung compliance (p = 0.006, OR = 0.7342) and driving pressure (p = 0.0058, OR = 1.6975) were influence factors for survival.
Conclusion: Lactate level, platelet count, lung compliance, and driving pressure are risk factors for survival.

Article Details

Keywords

Acute respiratory distress syndrome (ARDS), risk factor

References

1. Monchi M, Bellenfant F, Cariou A, et al. Early predictive factors of survival in the acute respiratory distress syndrome. A multivariate analysis. Am J Respir Crit Care Med 1998;158:1076-81.
2. Aisiku IP, Yamal JM, Doshi P, et al. The incidence of ARDS and associated mortality in severe TBI using the Berlin definition. J Trauma Acute Care Surg 2016;80:308-12.
3. Amato MB, Meade MO, Slutsky AS, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med 2015;372:747-55.
4. Force ADT, Ranieri VM, Rubenfeld GD, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA 2012;307:2526-33.
5. Steinvall I., Bak Z., Sjoberg F. Acute respiratory distress syndrome is as important as inhalation injury for the development of respiratory dysfunction in major burns, Burns 2008, vol. 34, No. 4, pp. 441-451.
6. Belenkiy S.M., Buel A.R., Cannon J.W., et al. Acute respiratory distress syndrome in wartime military burns: application of the Berlin criteria. Journal of Trauma and Acute Care Surgery 2014, 76(3), pp. 821-827.
7. Chaomin Wu, Xiaoyan Chen, Yanping Cai, et al. Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Intern Med. 2020;180(7):934-943.
8. Wu WH, Niu YY, Zhang CR, et al. Combined APACHE II score and arterial blood lactate clearance rate to predict the prognosis of ARDS patients. Asian Pac J Trop Med 2012;5:656-60.
9. Sheu CC, Gong MN, Zhai R, et al. The influence of infection sites on development and mortality of ARDS. Intensive Care Med 2010;36:963-70.
10. Qingqing Dai, Sicong Wang, Ruijin Liu, et al. Risk factors for outcomes of acute respiratory distress syndrome patients: a retrospective study. J Thorac Dis 2019;11(3):673-685.
11. Huber W, Findeisen M, Lahmer T, Herner A, et al. Prediction of outcome in patients with ARDS: A prospective cohort study comparing ARDS-definitions and other ARDS-associated parameters, ratios and scores at intubation and over time. PLoS One. 2020; 15(5): e0232720.